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GL: September Discussion


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Surprisingly, I found this on cancer drugs and fertility. It doesn't really bolster the Reva pregnancy story, but it's interesting nonetheless:

Breast Cancer Drug Not for Fertility

Femara May Cause Birth Defects; Risk Already Noted on Product

By Miranda Hitti

WebMD Health NewsReviewed by Louise Chang, MDNov. 30, 2005 -- The drug company Novartis is warning women not to take its drug Femara to boost fertility because of the potential risk of birth defects.

The drug company's Canadian branch is sending letters to Canadian fertility specialists about the risk, which isn't new and is noted on Femara's product information.

"A similar letter is expected to go out by the end of this week in the U.S.," says Kim Fox, director of global public relations for Novartis Oncology. Letters will be also sent in other countries, Fox tells WebMD.

Not Approved for Fertility Use

Femara isn't intended for use in fertility treatments. It's only approved for use by postmenopausal women with breast cancer.

Femara's labeling warns women not to take the drug if they are pregnant, might become pregnant, or are breastfeeding.

Femara is an aromatase inhibitor. It curbs production of estrogen, a female sex hormone which fuels some (but not all) breast cancers.

Fox says Novartis doesn't know how commonly Femara has been used for fertility. She says the company's worldwide safety database has records of 13 patients who have used the drug for that unapproved purpose -- known as "off-label" use.

The database just notes those patients' off-label use of Femara, not the outcome of any pregnancies they may have had.

Novartis' letter to Canadian fertility doctors appears on the web site of Health Canada, the Canadian health agency.

The letter came after Canadian researchers presented findings on Femara's off-label fertility use. The study by Marinko Biljan, MD, MRCOG, and colleagues was presented on Oct. 18 in Montreal at the annual meeting of the American Society of Reproductive Medicine.

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Let's see if we can jump start this thread with a little game of "Caption-this!" with some pics from today's show, I'll start:

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Alexandra: "What fresh hell is this? Where's my study? Where's my real furniture? Where are my servants? Why the heck is there a cheap plywood spiral staircase in my once glorious study?!"

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Frank: "Cyrus, Cyrus, Cyrus. You're days of double-dipping my daughter and sister are over. Your new girlfriend ain't gonna be a Cooper. In fact, she ain't even gonna be a girl, jailbird!"

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Dinah: OMG Grady, you reek. The last time we did the nasty it took me three Haz-mat showers to feel half-way clean. You are showering from now on. Let's shake on it."

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Cyrus: "Didi, you're wasting your time making him take regular showers, they just don't cut it. The only thing that works on Grady is being dipped in tomato juice like somebody who's gotten sprayed by a skunk."

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Alexandra: "Well, it looks likes you and little Bill are having a grand old time."

Lizzie: "You have no idea, Aunt Alex, no idea."

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Cyrus: "You smell that fresh air? I told you, Didi, tomato juice."

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Dinah: "I still can't smell any difference."

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Cyrus & Cassie, thinking to themselves: "Yup, we are sooooooooooooooo gonna boink each other again....and soon! Where's the nearest barn?"

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:( I feel your pain. But I hate your banner. Can we still be friends?

I watched Alex and Lizzie scenes and they made me sad and happy at the same time. Alex and Alan have had probably the most cantakerous sibling rivalry I've ever seen on a soap, and yet they've always been siblings who loved and looked out for each other and when push came to shove -- they were always the first to be most frmly planted on their sibling's side, no matter what. That's actually remarkable on soaps these days. Marj made me feel her pain. Why oh why aren't the vets used in a more effective way.

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Going on 2 weeks GL-less and haven't missed it at all.

I think my sister still watches from time to time. She said Thursday's episode was good, and I still have it on the DVR, but I haven't watched it yet.

Reading that article over on marlenadelacroix.com made me actually miss the days of Paul Rauch. Who'da thunk it. :huh::huh::huh:

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Well Greg, you missed a doozy on Monday. lol. Alan is in a coma because of some kind of brain disorder and in his hospital room, he has Rick, Alex, Bill, Lizzie and maybe others (I forget now) in there, and they all start yelling at Alan to wake up. And he did. It was cringeworthy. Very embarassing for the actors.

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