Aren't they supposed to be in Echo Park?
It may be a case of trying to tackle too many issues at once but I believe Echo Park has been undergoing some pretty radical changes with gentrification and some of that was mentioned in the previous season.
(Also, Schneider who manages the building is somewhat symbolic of the very hipster that is gentrifying the neighborhood, although they obviously love him and he's a part of their lives- he likely represents the positive side of gentrification )
Also, I think that showrunner lived in Echo Park and perhaps feels like setting the show there, she can draw on her personal knowledge of the area so that her characters feel more realistically grounded in a specific place, rather than writing generalities about somewhere abstract or somewhere she doesn't know that much about.
When I write, I like to be as specific as I can, the writing feels more genuine to me.
One complaint I had about a show like Friends was despite the fact that they were supposed to be set in NYC, it didn't truly feel like NYC. I still enjoyed the show but that aspect grated a little.