Considering she (presumably) hasn't been mentioned in donkey's years, I like to think she's disowned them all. Maybe she's the killer, then?
The children can survive, I'm not a monster. Their last names are Sugden which is a good start. Andy can come back and take care of them since we're playing fan-fiction. Daz too, after Adam briefly returns to get closure with Victoria after Moira is forced to turn herself in for Emma's murder by the killer. Adam takes Isaac with him. Scott and Kelly return and change April's name to Windsor. Samson and Lydia are run out of town, getting a rare reprieve from the killer. Ross retrieves Moses. Charity, with help from Jamie, convinces Kim to protect Noah, reclaiming his Tate name once more. Liv can move in with Victoria. Rhona and Paddy get the hell out of dodge with their sproggs. We really just need to make sure the Dingle name itself is squashed once and for all.
As for the killings themselves, I would start with Cain. He's done the most damage. He gets the most brutal death. Jasmine returns to help Debbie cope and they reunite, until Debbie is murdered. Jasmine leaves town heartbroken. Sam's death would be gentle. Charity gets the most epic death. Mandy and Marlon's deaths are swift to avoid their wailing for our benefit. Aaron and Chas die together. Belle's voices come back and convince her she's the killer so she kills herself. End with Zak.
Okay, I don't if know I missed anyone but I think I'm done with this craziness now.