On AMC 2.0 David and Angie got even closer, and Jesse (who became semi-estranged from Angie due to a cover-up while trying to save Cassandra; it was another lie on top of a long list of lies from Jesse at the end of the ABC run) grew deeply insecure about their connection.
It was gonna happen, dammit! And IMO it had to come in part from Agnes. She was allegedly heavily involved in the final months on the network, which is when I think Angie gave David an impassioned speech about his being a good man. She was then also involved at Hulu, where I think there was initially a complete writing team turnover. Except for her.